Ethyl 4-(3-chlorophenyl)-3,6-dihydroxy-6-methyl-2-(2-pyridyl)-4,5,6,7-tetrahydroindazole-5-carboxylate
نویسندگان
چکیده
In the title compound, C(22)H(22)ClN(3)O(4), the cyclo-hexane ring adopts a twisted half-chair conformation. The mol-ecule is stabilized by an intra-molecular O-H⋯N inter-action, generating an S(6) motif. The crystal packing is stabilized by inter-molecular O-H⋯N and C-H⋯O inter-actions.
منابع مشابه
Ethyl 7-chloromethyl-5-(2-chlorophenyl)-7-hydroxy-2-methylsulfanyl-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidine-6-carboxylate
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In the title compound, C(17)H(20)N(2)O(4)·H(2)O, the cyclo-hexene ring adopts a half-chair conformation while the indazole ring is essentially planar [maximum deviation = 0.0192 (12) Å]. In the crystal, pairs of inter-molecular O-H⋯N hydrogen bonds link the mol-ecules into dimers lying about inversion centers and intra-molecular O-H⋯O hydrogen bonds result in six-membered rings. The dimers are ...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010